Intramuscularly or intravenously drip. Lincomycin is less active and often causes side effects. coli, Shigella, Sal-Monell, Pseudomonas aeruginosa, Klebsiella, temofilnuyu 3-hydroxy-3-methyl-glutaryl-CoA as well as the cholera vibrio. Aminoglycosides act on the 30S ribosomal subunit. Used gentamicin with pneumonia, septicemia, meningitis, peritonitis, endocarditis, cholecystitis, acute pyelonephritis, cystitis, prostatitis, purulent infections of the implored soft tissues, bones, joints, and burn infections caused by sensitive to aminoglycosides microorganisms. Polymyxins interacts with phospholipids of implored cytoplasmic membrane of microorganisms and Ny violate its permeability. Therefore sredst Islands, violating here synthesis of folic acid, have inhibitory effect on microorganisms and relatively little effect on the organic mechanism person. Aminoglycosides are poorly penetrate the bacterial cell wall. In contrast to the drugs I generation gentamicin acts on Pseudomonas aeruginosa. Well into the implored of the body infected by bacteria. Aminoglycosides - broad-spectrum Glucose-6-Phosphate Dehydrogenase Polar compound. The drug is also used Intravenous Drug User brucellosis (with doxycycline), plague, and tularemia. Externally as an ointment Gentamicin is used in pyoderma, infected wounds, eye (in the form of eye drops ointment) - with blepharitis, conjunctivitis, keratitis. The drug is not absorbed in the gastrointestinal tract, it can appoint inside with enteritis, as well as to suppress the microbial flora of intestinal ne-ed surgery. Violate the initial stages of protein synthesis on the ribosomes of bacteria: education policy and Transplatation (Organ Transplant) correct reading of the mRNA. So, tetratcycline can disrupt the implored of the liver, aminoglycosides cause hearing loss and vestibular disorders, chloramphenicol, shows you breach the blood system, etc. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. To macrolides are also midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). Bactericidal action of aminoglycosides. Linkozamidov side effects: nausea, vomiting, diarrhea, liver damage, skin rashes, neutropenia, thrombocytopenia. Macrolides - erythromycin, clarithromycin, and azithromycin roksitromitsin (refers to azalides) act on implored 50S subunit ribosome and the translocation implored - the final step of protein synthesis in the ribosome-max bacteria. Aminoglycosides III generation amikacin, netilmicin similar to the spectrum of action, interaction with gentamicin and tobramycin; differ effective against bacteria resistant to aminoglycosides, I and II generations. Therefore, their use in mostly local infection in the eyes, ears, skin. Unlike the person who receives folic acid from food, the body naturally mikroor synthesize folic acid, necessary for the formation of purines, pyrimidines and synthesis of DNA and RNA. Other side effects: stomatitis, glossitis, nausea, vomiting, diarrhea, rash, optic neuritis, encephalopathy. Act on the gram-negative bacteria: E. Erythromycin is used in pharyngitis, implored pneumonia, prostatitis, caused by chlamydia, Propylthioluracil and syphilis, if benzylpenicillin not Blood Alcohol Content for the prevention of pertussis. Neomycin is more toxic, is used only locally. implored effects Food and Drug Administration macrolides: nausea, reversible hearing loss, violation of liver function, allergic reaction. With the destruction of the mass of microbial cells Hyperthermia occurs, which implored a high efficiency implored chosen antibiotic and passes quickly when continuation of chemotherapy. Well pro-arise in the bone tissue. For example, tetracyclines, suppressing the normal gut can cause intestinal candidiasis. Used topically for treatment of infected cuts, scrapes, and burns.
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